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The fda reviewed approved colchicine for gout flares, awarding colcrys a three-year term of market exclusivity, prohibiting generic sales, and increasing the price of the drug from 0.

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Treated plants must be watched carefully to look for colchicine effects.

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Byzantinum , another plant of the colchicaceae family, resulted in its efficient absorption by colchicine.

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, as well as the 40 increase in systemic levels of colchicines observed with concomitantly administered fluconazole a moderate cyp3a4 inhibitor that is not known to inhibit p-gp in a drug-drug interaction study, the drug-drug interaction potential of colchicine with strong or moderate cyp3a4 inhibitors that do not inhibit p-gp cannot be ruled out completely.

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cases of myopathy, including rhabdomyolysis, have been reported with hmg-coa reductase inhibitors, including rosuvastatin, coadministered with colchicine, and caution should be exercised when prescribing rosuvastatin calcium with colchicine see warnings and precautions .